| Purpose:To investigate the therapeutic effect by ways of tonifying the kidney and fortifying the Governing vessel function in the treatment of ankylosing spondylitis(AS).Method:The qualified patients for this study were all diagnosed with ankylosing spondylitis of the deficient kidney-yang syndrome,and were treated according to the principle of tonifying the kidney and fortifying the Governing vessel function by prescribing the jinkuishenqiwan concoction.In all 40 qualified subjects,the before and after treatment symptoms were observed.The curative effect of the method was assessed according to the Assessment of Ankylosing Spondylitis(ASAS) and The Chinese Medicine Syndrome Effectiveness Guideline.Results:1.ASAS Assessment:After the first month of treatment,of the 40 patients, only 16 scored ASAS20(40%) and none scored above ASAS50 or ASAS70.At the end of the third month,there were 13 patients who scored ASAS20(35%),16 patients scoring ASAS50(40.0%) and 2 patients scoring ASAS70(5%).At the end of 6 months of treatment,there were 4 patients who scored ASAS20 (10.0%),25 patients scoring ASAS50(62.5%) and 6 patients scoring ASAS70 (15.0%).2.Chinese Medical Syndrome Assessment:After the first month of treatment,there were 22 patients(55%) who had effective results and 18 (45%) who were ineffective;the total effective rate was 55%.After the second month,there were 11 patients(27.5%) who had very effective results, 24(60%) who were effective and 3 ineffective(30%);the total effective rate increased to 92.5%.3.Other Major Indices Observed:After one month of treatment,the degree of pain,their own and the doctor' s assessment regarding their medical condition were significantly improved as compared to before the treatment (p<0.05).However,the change in BASDAI and BASFI scores was not statistically significant(p>0.05).Further,at the end of third and sixth months of treatment, all indices improved significantly(p<0.05).Conclusions:Treating ankylosing spondylitis by ways of tonifying the kidney and fortifying the Governing Vessel function is shown to be effective in controlling and relieving clinical symptoms,which indicates that the method can decrease the degree of inflammation thus allowing better joint mobility and function. |