Clinical Diagnosis And Treatment Analysis Of 10 Cases Solid-pseudopapillary Tumor Of Pancreas

Solid-pseudopapillary tumor of pancreas(SPTP)is a Is a low degree of malignancy or borderline tumor,some of them have invasion tendency,the incidence is low in clinical. Source of their organization and pathogenesis is currently no conclusive. In 2004 the World Health Organization formally named it as SPTP. The tumors contain a mixture of solid,cystic,and pseudopapillary patterns. In current years,with SPTP imaging characteristics and pathological features,immunohistochemical characteristics of in-depth,the reported cases in domestic is increase. However, clinical on this rare tumor of the pancreas is still not deep enough understanding of, the majority of postoperative pathology confirmed the diagnosis. Nowadays,at home and abroad there is no clear standard to solve the problem of diagnostic criteria and the specific choice of surgical procedures,Misdiagnosis, misdiagnosis is not uncommon for. We retrospectively analyzed 10 cases of SPTP diagnoised between 2003 and 2009 in the Clinical Hospital of Jilin University, Analysis of pancreatic tumor from other SPTP special clinical, paramedical examination, pathological features,in order to discuss about the SPTP the clinical characteristics and treatment methods, Improve clinical diagnosis and treatment effect, Reduce the occurrence of postoperative complications.Objective: To discuss the Clinical features of solid-pseudopapillary tumor of pancreas, to enhance the understanding of the diagnosis and treatment.Methods: The clinical materials of 10 cases solid-pseudopapillary tumor of pancreas treated in Third Hospital of Jilin University between 2003 and 2009 were analysed retrospectively.Results: Statistics Solid-pseudopapillary tumor of pancreas of 10 cases, 2 cases of male, female 8 cases, male to female ratio was 1:4; the age of 13-58 years old, median age 27 years; all are single pathological tumor, located in pancreatic head those three cases, accounting for 30%, is located in pancreatic body in 2 cases, accounting for 20% of those at the rear of 5 cases of pancreas, accounting for 50%; tumor diameter <5.0 centimeters in 3 cases, 5 cm -10 cm 7 cases, accounting for 70%. Clinical data of the five cases (50%) no obvious clinical symptoms, abdominal mass discovered accidentally or by abdominal ultrasound examination found that there is intra-abdominal space-occupying changes in three cases (30%) as mild symptoms of abdominal pain, 2 cases (20%) accompanied by abdominal discomfort for more than nausea, vomiting treatment. Hospital routine examination and tumor markers were not found.All the 10 cases of abdominal ultrasonography, 6, a routine abdominal CT examination, abdominal ultrasonic diagnosis in line with the rate of 30%, CT diagnosis rate of 16.7%. All patients underwent surgical treatment, application of a simple tumor surgery two cases, the application to retain the head of pancreas duodenal resection in 1 case, the application of pancreatic tail resection, pancreas - Campylobacter invagination pancreaticojejunostomy with circle discontinuous U suture in 2 cases, middle pancreatectomy, pancreatic tail jejunal Roux-en-Y anastomosis in 1, pancreatic body and tail of four cases of joint splenectomy. 1 cases of postoperative patients with mild acute pancreatitis with acute complications, 1 patient had pancreatic fistula; cases in this group all the 10 cases of patients followed up for 3 to 70 months, with an average follow-up of 30 months, 10 patients were the restoration of good, does not affect the normal work and daily life, no long-term complications after abdominal ultrasound periodic review no tumor recurrence and metastasis.Conclusions:solid-pseudopapillary tumor of pancreas have lower clinical incidence,in young women with multiple, non-specific clinical manifestations, physical examination is an effective method of early detection, diagnostic imaging guidance. Uncertain parts of tumor growth, the head of pancreas, pancreas body, pancreas tail can occur. Treatment of choice for surgery, specific surgical technique of choice should be based on the location of the tumor findings, the manner in which the growth and invasion, but the light of the rapid intraoperative pathological findings, such as cancer pathology results will need to consider the appropriate scope of the expansion of the operation.