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Studies On Lipophilic Chemical Constituents In The Hedyotis Diffusa Wild

Posted on:2010-03-25Degree:MasterType:Thesis
Country:ChinaCandidate:Y N ZhangFull Text:PDF
GTID:2144360272497586Subject:Medicinal chemistry
Abstract/Summary:PDF Full Text Request
Rubiaceae Hedyotis diffusa for annual herbs Hedyotis diffusa Hedyotis diffusa Wild. full of dry grass, bitter sweet and warm, non-toxic. By the study shows that a large number of Hedyotis diffusa bioactive substances, including anthraquinones, terpenoids, flavonoids, steroid alcohols, alkanes, organic acid, polysaccharides, such as chemical composition. Hedyotis diffusa drugs commonly used for civil, modern research shows that it has a wide range of pharmacologicalactivities, in particular, to enhance the immune and the most prominent anti-tumor activity, indications for respiratory tract infections, pneumonia, tonsillitis, gallbladder inflammation, appendicitis, postoperative infection and cancer adjuvant therapy. In order to meet clinical needs, have a significant social and economic benefits should diffusa-depth development, research, or an effective part of the active ingredients, and explore its mechanism, the development of its new formulations and indications, so white in this experiment snake tongue grass Progress on the basis of the chemical composition of their further studies.In this paper, macroporous resin, silica gel column chromatography separation means such as through physical and chemical constants and spectral dataanalysis methods, from traditional Chinese medicine has been diffusa 5 monomer compounds. Are as follows:β-sitosterol, 2-hydroxy -1- methoxy-anthraquinone, and p-coumaric acid, deacetyl Mukdenia car methyl glucoside, 2-hydroxy-3-methyl anthraquinone.Hedyotis diffusa Canton drug source, the price low, fewer side effects, widely used and effective. We can further research the active ingredients, the development of high efficiency and low toxicity of new drugs; enhance the pharmacological studies, clinical applications and reasonable to provide a scientific basis.
Keywords/Search Tags:Hedyotis diffusa, fat-soluble chemical composition, structure identification
PDF Full Text Request
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