Purpose:To investigate the therapeutic effect of chemistry ablation(PEI)combined with transcatheter arterial chemoembolization(TACE)in treating primary hepatocellular carcinoma.Methods:To collect a total of 89 cases of primary hepatocellular carcinoma patients, 4 patients were lost, do not take part in grouping statistics. 85 cases of patients with primary hepatocellular carcinoma, 60 cases of right upper quadrant pain was admitted to hospital, for medical examination found 25 cases of intrahepatic space-occupying lesions. Grouped according to the principle of single-date and double-date law, divided into TACE group and combined therapy group. One of 54 cases of pure TACE group, and the combined therapy group were 31 cases of patients 2 weeks after TACE treatment of PEI. TACE alone group and combined therapy group 1~1.5 per month to carry out duplicate treatment, continuous treatment of duplicate 3 times for a course of treatment, all patients had a complete course of treatment. After the completion of a course of treatment, 1.5 per month CT follow-up visit one time, if stable condition, every 3~6 month CT examination, when necessary, DSA inspection trip.Results:In TACE group, the complete necrosis rate of tumor was 20.37%; one year and two year survival rate were 72.22%?46.30%; peripheral vessels of neoplasma reproduce rate was 79.63%; the recurrence rate after a course of treatment was 48.15%; the rate of AFP reduce after treatment 53.19%. Respectively corresponding value were 80.65%; 83.87% ? 54.84%; 32.26%;5.81%; 78.57%in therapeutic alliance group. There were significant statistical differences between the two group (p value smaller than 0.01) Conclusion:chemistry ablation combined with transcatheter arterial chemoem- bolization treatment of hepatocellular carcinoma was superior to pure TACE group, is a safe, effective, more economic, more in line with the clinical treatment study of integrated programs. The two groups the complete necrosis rate of tumor; one year and two year survival rate; peripheral vessels of neoplasma reproduce rate; the recurrence rate after a course of treatment; the rate of AFP reduce after treatment with a significant difference. PHC in the larger treatment should not place undue reliance on TACE surgery should be the comprehensive application of transcatheter arterial chemoembolization and percutaneous ethanol injection and neonatal kill residual tumor cells in order to improve efficacy. Each other to make up for both, so that the larger the complete necrosis of hepatocellular carcinoma was significantly increased, thereby further enhance the therapeutic effect of hepatocellular carcinoma.
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