An Experimental Study Of The Efficacy Of A Deproteinised Cancellous Bone Combined With BMP And Fibrinin Healing Of Rabbit Segmental Radial Defect

A Experimental Study of the Efficacy of a deproteinised cancellous bone combined with BMP and fibrinin Healing of Rabbit Segmental Radial Defect//Deng Gang, Liu Xing-yan,Chen Ke-ming,Bai Meng-hai,Zhang Xu-yuan et al.Clinical Medical College of LanZhou University,Lanzhou 730000.Abstract Purpose:To repair segmental bone defect with the composite of deproteinised cancellousbone,bone morphogenetic protein(BMP)andfibrin.Methods:Bone defects were createdin 36 New Zealand rabbits on the bilateral Radius and were treated with three kinds of implantations:A,Composites of deproteinised cancellous bone,BMP and fibrin;B,deproteinised cancellousbone;C,nothings control.The defects were observed through entgenograph,opticalmicroscopeobserving, electronmicroscope scanning,at 2,4,8,12,16 weeks.Results:The defects treat with A implantation regenerated much more new bone and bridged earlier than the defects treated with B implantation and were repaired satisfyingly 16 weeks after operation.The defects with B and C implantation couldn't get osseous tissue healing. Conclusion:The composites of deproteinised cancellousbone,bone morphogenetic protein(BMP)and fibrin can be used effectively to repair segmental bone defect.