| Objective: To investigate sensibiligen state of different degree of bronchial asthma in children and guide the clinical prevention and cure.Methods: 73 children (age range, 3～12 years) with different degree of bronchial asthma were included in the study, and all children had their serum total IgE and specific IgE antibody of sensibiligen measured with enzyme linked immunosorbent assay.Results: The positive rate of general serum IgE antibody in all children were 65.8%; All 48 children who positive in general serum IgE are positive in specific IgE, however, 22 of other 25 children who negative in general serum IgE are positive in specific IgE; The positive rates of house dust and acarid are most high in all specific IgE antibody of different sensibiligen, and their positive rates were 74.0% and 63.0%, respectively; There was statistically significant difference in serum total IgE between different group(X2 =37.7869,P<0.0001); There was statistically significant difference in different sensibiligen between different group (X2 =20.8437,P= 0.0001). Conclusions: This study indicates that bronchial asthma is very associated with sensibiligen, and specific IgE is more sensitive and direct for the detection of bronchial asthma in children. House dust and acarid are primary motivation of asthmatic attack in children. The degree of bronchial asthma in children is positive correlation with serum total IgE level. Moreove, the patients who had positive in specific IgE antibody of various antigens are common more severe in the pathogenetic condition.
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