Bipolar affective disorder, which is abbreviated with bipolar disorder, is characterized with both mania phase and depression phase insult simultaneously or alternately. Bipolar depressive disorder is a kind of bipolar disorder which is in depressive phase. Its therapeutics is complicated owing to complexions symptoms, bad reaction to drugs, and risk of turning into manic phase. Therefore, it's urgent to summary experiences and lessons during clinical occupation to form a norm of therapeutic regimen. Here we present three cases of bipolar depression patients diagnosed in the department of psychiatry of the Second Affiliated Hospital of Zhejiang University.
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