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Analysis The Relation And Distribution Between The Relative Data And Diabetic Peripheral Neuropathy's Type In Traditional Chinese Medicine

Posted on:2009-06-06Degree:MasterType:Thesis
Country:ChinaCandidate:Y Y ZhouFull Text:PDF
GTID:2144360245950327Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Objective:1. Integrate the theory of Traditional Chinese medicine, analyse the distribution of diabetic peripheral neuropathy ' s type in Traditional Chinese Medicine.2. People can understand the dangerous factors of diabetic peripheral neuropathy according to compare and analyse the relational data and factors of the diferent discriminate the type in Traditiona Chinese Medicine.Methods:116 cases of diabetic peripheral neuropathya dmitted in the Guangzhou hospital of Traditional Chinese Medicine from June, 2007 to May, 2008 have been classified as the syndrom blood stasis due to deficiency of qi group,syndrom blood stasis due to deficiency of yin group,syndrom of blood stasis blocking collatera,syndrome of deficiency of both liver and kidney group with the Guideline of Diabetes Mellitus in Traditiona Chinese Medicine edited by China Association of Chinese Medicine in 2007.Record the relational data such as sexual,age,the course of diabetes mellitus, FPG (fastingp lasmag lucose),HbA1c,total plasma cholesterol,triglyceride,high density lipoprotein,low density lipoprotein,high sensitivity C-reactive protein and vascular endothelin.The cases of syndrom blood stasis due to deficiency of qi group,syndrom blood stasis due to deficiency of yin group, syndrom of blood stasis blocking collatera, syndrome of deficiency of both liver and kidney was compared each other. A computer Package of SPSS Advanced Statisticsl3. 0 was used to an alyse the data. All the continuous variables are presented as mean±SEM. We used one-way ANOVA test and a Student t test to estimate relationships of the enumeration data, chisquare analysis was employed to estimate the measurement data, and did relational analysis.Results:Compared with other grops syndrome of deficiency of both liver andkidney group has longer course of diabetes mellitus and has statistically significance (P<0. 01).The syndrom of blood stasis blocking collatera was higher in fasting plasma glucose (FPG) level and has statistically significance(P<0.05).The syndrom of blood stasis blocking collatera and syndrome of deficiency of both liver and kidney group were higher than other two groups in HbA1C, and have statistically significance.The CHOL of syndrom of blood stasis blocking collatera group was higher than syndrom blood stasis due to deficiency of qi group,syndrom blood hstasis due to deficiency of yin group,syndrome of deficiency of both liver and kidney group and have statistically significance (P<0. 01, P<0.05, P<0.01).The TG of syndrom blood stasis due to deficiency of yin group was higher than theother 3 groups, but the difference has no statistically significance.HDL-C of syndrom blood stasis due to deficiency of qi group was lower than syndrom blood stasis due to deficiency of yin group,syndrom of blood stasis blocking collatera,syndrome of deficiency of both liver and kidney group, and the difference has statistically significance (P<0. 01, P<0.01, P<0.05).LDL-C of syndrom blood stasis due to deficiency of yin group was higher than syndrom blood stasis due to deficiency of qi group,syndrom of blood stasis blocking collatera,syndrome of deficiency of both liver and kidney group, and the difference has statistically significance (P<0.01, P<0. 01, P<0.05).Hs-CRP and ET-1 of syndrom blood stasis due to deficiency of qi group was higher than the other 3 groups, but the difference has no statistically significance.In the types of diabetic peripheral neuropathy, according to the proportion from high to low are the syndrom of blood stasis blocking collatera,syndrom blood stasis due to deficiency of yin,syndrom blood stasis due to deficiency of qi,the end is the syndrome of deficiency of both liver and kidney, but the difference of type between men and women has no statistically significance.Conclusion:The diabetic peripheral neuropathy is one of the chronic complications of diabetes mellitus. Not only increase the financial burden of patients with diabetes mellitus, but aslo impact on the quality of life of patients with diabetes mellitus. Diabetic peripheral neuropathy was a disease with complex factors.Western medicine confirmed that vascular damage, metabolic disorders, etc. are the main reasons, the course of diabetes mellitus,metabolic disorders in glucose and lipid are factors of diabetic peripheral neuropathy.Traditional Chinese Medicine considered that the blood stasis and olaterals block was the main reason of diabetic peripheral neuropathy, the deficiency of yin was the key to the disease, the deficiency of qi was crux to the disease, the deficiency of yan is the inevitable trend of the disease development.Therefore, it is important to prevent the progress of the diabetic peripheral neuropathy. If it is treated in early, we can effectively prevent and control the occurrence and development of diabetic peripheral neuropathy.In clinical practice we must use the advantages of Traditional Chinese Medicine, insist the differential treatment in Traditional Chinese Medicine, and this is the important measure to treat diabetic peripheral neuropathy.
Keywords/Search Tags:Diabetes Mellitus, Diabetic peripheral neuropathy, TCM type
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