The Study Of Correlation Between The Classification Of TCM On Coronary Disease And The Function Of Endothelium Of The Vascular

Purpose: This topic pass a clinical research, study correlation between the classification of TCM on coronary disease and the function of endothelium of the vascular. then analyze the NO and ET—1 level of 131 dissimilarity Chinese medicine classification of coronary disease, To observe variety regulation of which each Chinese medicine symptoms of coronary disease and ET-1/NO, and evaluating value which ET-1/NO be objective index sign in judging importance degree of classification of TCM on coronary disease. To provide modern medical science standard for the sake of dialectics cent type in coronary disease. Method: First, to select 131 examples of coronary patients who come from cardiovascular section of the Chinese medicine hospital in Guangzhou city. and whom must bu up to the diagnosis standard which established by WHO in 1999. Second, to record name, sex, age, height, weight, blood pressure of each example, and draw blood measuring the NO and ET level. Grade point the Symptoms of The chest pain, chest are stuffy, heart palpitates, the spirit be short. These patients were divided into 4 sets according to the standard of《chest Bi deplore greatly the certificate cure with research》which was revised by the medicine administration of the nation Chinese medicine. Add up to four certificate types: The strenuous effort Yu Zu type, the phlegm Zu heart vein type, the debility blood Yu type,spirit Yin two falsely type etc. Last, to statistics and analysis the datas, for making first step of relativity analysis, then Lead a conclusion.Result: Among the selections of 131 examples, male 67, female 64, age 50—83 years old, average 61.48±5.73 years old; the strenuous effort Yu Zu type is 37, the phlegm Zu heart vein type is 34, the debility blood Yu type is 27, spirit Yin two falsely the type is 33. The course of illness of diabetes are 5—32 year, average 11.3±6.85 years. High blood pressure course of illness are 8—40 year, average 15.9±9.67 years. Each set has no statisticsdifference and Can ratio each other.The blood plasma level of ET-1 of coronary show more higher than the matchedcontrol, (P<0.05), but the NO level be lower than the matchedcontrol, (P<0.05);the ET-1 level between foue sets from high to low: SpiritYin two falsely type> The phlegm Zu heart vein type> The strenuous effort YuZu type> The debility blood Yu type, but the NO level show the contraryresult. The ET-1 level of Heavy degree of CHD show Obvious higher than the lightdegree's, (P<0.05), But to the NO is contrary too, (P<0.05).Conclusion: The measurement of blood plasma ET-1 and NO is Independent andcredibility as an index sign which use to estimate the CHD. Among fourclassifications of TCM on coronary disease, ET-1 with spirit Yin two falselythe type goes up most obvious, secondly The phlegm Zu heart vein type, then theStrenuous effort Yu Zu type and the debility blood Yu type; contraryly to theNO. Among them the ET-1 level of strenuous effort Yu Zu type and the debilityblood Yu type comparison do not show obvious difference, but the NO level ofthe strenuous effort Yu Zu type and the phlegm Zu heart vein type show littledifference too. This research provide an objective reference for the Chinesemedicine dialectics' theory cure theories, Also provide theory basis foradopting therapy of the benefit spirit keep Yin to coronary disease as earlyas possible.