| Hepatocellular carcinoma is one of the most important cancer and the operation is the best treatment of hepatocellular carcinoma. However, The current treatment of HCC depends on several factors, including the size of the lesion, number of lesions, presence of metastatic disease, and remaining liver function. Thus, there is only a few of them whom are suit for operation. And other treatments of HCC, such as chemotherapy and radiotherapy, can not lead to a satisfactory outcome. Resent years, many minimally invasive techniques have been improving, such as RFA, alinjection, refrigeration. And the RFA is a minimally invasive, safe, economics, repeatability treatment. So The use of radiofrequency ablation (RFA) to treat both primary and metastatic hepatic disease continues to expand. However, the role of RFA has yet to be clearly defined in patients who are still considered amenable to surgical intervention. Future prospective studies are needed to define whether RFA can be used as an alternative to surgery in certain patient populations. Now, does radiofrequency ablation technology will continue to serve as a palliative curative intervention for individuals with hepatic tumors or it can replace some hepatectomy, there is also some contention. In this paper, we briefly explain RFA and discuss its use in HCC and metastatic disease to the liver.
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