To Inject Oxoygen-Ozoen Into The Facet Joints Capsule To Enhance The Curative Effect Of Minimally Invasive Oxygen-Ozone Therapy For Lumbar Disk Herniation

Objective: Oxygen-ozone therapy is a minimally invasive treatment for lumbar disk herniation that exploits the biochemical properties of a gas mixture of oxygen and ozone. We assessed the therapeutic outcome of oxygen-ozone therapy and compared the outcome of administering medical ozone in lumbar intradiscal with the outcome of medical ozone followed by injection of oxygen-ozone in lumbar intradiscal and the same session facet joints capsule.Methods: Thirty-two patients presented with clinical signs of lumbar disk nerve root compression and low back pain, with CT and/or MRI evidence of contained a single session disk herniation. All were randomly divided control group (group D) and experimental group (group F), each group had sixteen patients. Sixteen patients (group D) received lumbar disc injection of an oxygen-ozone mixture at an ozone concentration of 60ug/mL and foramen intervertebrale (periganglionic) injection of an oxygen-ozone mixture at an ozone concentration of 40ug/mL. The other thirteen patients (group F) received the same as group D, in addition, the facet joints of the same session injection of an oxygen-ozone mixture 10mL at an ozone concentration of 30ug/mL. To observe the preoperative conditions of the patients including of low back pain and numbness leg and the adverse events in operation. Therapeutic outcome was assessed at the 1st, 2nd and 3rd month after treatment by recovery of low back pain, leg pain and leg paralysis. After 3 months, a MacNab method was evaluated therapeutic outcome. Results were evaluated by two observers blinded to patient distribution within the two groups.Results: In group D, treatment was a success (excellent or good outcome) in 87.5% which was excellent in 50% and good in 37.5%. In group F, treatment was a success in 87.5% which was excellent in 75.0% and good in 12.5%. The difference in excellent or good outcome between the two groups was statistically significant. The difference of adverse events incidence was not statistically significant between the two groups.Conclusion: The outcome of medical ozone followed by injection of oxygen-ozone in lumbar intradiscal and the same session facet joints was better chan the outcome of administering medical oxygen-ozone in lumbar intradiscal. Administering ozone in facet joints could relieve low back pain. And to increase the quantity of oxygen-ozone could not raise the incidence of adverse events.