The Analysis Of Changes In Traditional Chinese Medicine Types Of Syndromes Of Helicobacter Pylori-associated Gastritis Before And After Triple Therapy

Background:Helicobacter pylori-associated gastritis(HpAG)is a common and frequently-occurring disease,it is easy to recur and hard to healing.Up to date,H.pylori infection was accepted as the major pathogenic factor of chronic active and peptic ulcers;Infection of H.pylori was related to the occurrence of gastric adenocarcinoma.The received method is triple therapy base on antibiotics and PPI/RBC.In recent years,the traditional Chinese medicine has made many researches on the HpAG syndrome-type and anti-Hp.There have very important significance to research the rule of the changes in traditional Chinese medicine type of syndrome of HpAG after triple therapy.Objective:Research the changes in traditional Chinese medicine types of syndromes of HpAG before and after triple therapy,and to analyze the influence of triple therapy to HpAG on traditional Chinese medicine types of syndromes.Methods:Through medical record material collection,we will conform to the HpAG patient which will bring into line with the standard.Treat according to the standard treatment,7 days for a course of treatment.Record patient' s symptom through four diagnostic methods and differentiate syndromes,hypothesis and establish corresponding type of syndrome statistical table,the enumeration data comparison to use the X~2 examination,the rank data uses the non-parameter statistical method,the measurement data uses the t examination or rank sum test,Software use statistics package(SPSS Version 15.0 for XP),which 0.05 expression has the significance.Results:1.Syndromes distribution of HpAG in Guangzhou and its peripheral regions is following:syndrome of spleen deficiency:24.0%(23/96);syndrome of stagnation of liver qi:13.5%(13/96);syndrome of yin deficiency:6.3%(6/96); syndrome of dampness-heat:42.7%(41/96);syndrome of static blood:5.2% (5/96);syndrome of deficient cold:4.2%(4/96);others syndrome:4.2%(4/96).2.The changes of syndrome of spleen deficiency and syndrome of dampness-heat before and after triple therapy were significantly different. Syndrome of spleen deficiency had significantly aggravated after triple therapy.3.The excess syndrome had significant increased and the deficiency syndrome had significant decreased after triple therapy.Conclusion:Traditional Chinese medicine types of syndromes of HpAG had changed after triple therapy and the syndrome evolution regularity transfers from the excess syndrome to the deficiency syndrome.Syndrome of spleen deficiency had significantly aggravated after triple therapy.