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Indoor Air Pollutants And Study On The Relationship Between Childhood Asthma

Posted on:2009-02-18Degree:MasterType:Thesis
Country:ChinaCandidate:H YanFull Text:PDF
GTID:2144360242999826Subject:Occupational and Environmental Health
Abstract/Summary:PDF Full Text Request
Objective: To study the adverse effects of indoor harmful effects on the impact of childhood asthma, and related factors, the impact on children with asthma screening the various risk factors, prevention and treatment to introduce measures to protect vulnerable children. Methods: A case-control epidemiological study design,through questionnaires collected 100 cases of children with asthma (case group) and 100 patients with non-asthmatic children (control group) information,the study of indoor air live in formaldehyde, carbon monoxide,carbon dioxide concentration and Comparing the two groups, as well as the extent (the rough, Jianzhuangxiu, refined decoration) of formaldehyde in indoor air, carbon monoxide, carbon dioxide concentration, the two groups of children with asthma symptoms and signs, using conditional logistic regression analysis, asthma in children may be influencing factors were analyzed.Results: Case Group of formaldehyde in indoor air concentration [(0.163±0.034) mg/m3],formaldehyde exceeding rate (66%) was significantly higher [(0.085±0.027) mg/m3,29%],refined decoration in the room Formaldehyde concentrations in the air [(0.150±0.035) mg/m3], formaldehyde exceeding rate (59%) was significantly higher than that Jianzhuangxiu [(0.114±0.023)mg/m3, 36%] and the control group (0.040±0.006)mg/m3,0]; will formaldehyde concentrations from low to high divided into four levels, level 1 as a reference group, we can see that the rest of the class in the patient group and control group in the OR of growing,adjusting for age, gender, family Do not, whether passive smoking, whether there is a family history of asthma,family history of allergies,allergic individual history after its corresponding OR values have also increased, while the trend in the OR indicates that after adjustment confounding factors, increased the average concentration of formaldehyde a class can make the risk of asthma increased by 2.48 and 2.33 times,the results showed that an increase of indoor formaldehyde concentrations of a unit,can be dangerous to children with asthma increased 0.12 times; formaldehyde concentrations >0.10 mg/m3 group irritating cough (χ2=9.021,P<0.05), a large number of present phlegm (χ2=7.190, P<0.05), dyspnea (χ2=18.404,P<0.05), a Wheezing auscultation Voice (χ2=32.641,P<0.05) was significantly higher than that formaldehyde concentrations≤0.10 mg/m3; single factor analysis showed that achieve significant levels of risk factors,including: formaldehyde indoor air pollutants (OR=2.22),passive smoking (OR=2.16), family history of asthma (OR=2.23),and the family history of allergies (OR=2.56), as well as the individual history of allergies (OR=3.44),indoor ventilation (OR=0.42), raising Plant (OR=0.44) is a protective factor, played on the indoor air purification role in the conditional logistic regression analysis, indoor air pollutants formaldehyde (OR=2.22), passive smoking (OR=2.96), family history of asthma (OR=2.48), and the family history of allergies (OR=2.23) and the individual history of allergies (OR=3.52) entered the final model. Conclusions: The high incidence of childhood asthma in addition to genetic factors, the most important thing is that indoor pollution (respiratory belt level) on the respiratory health of children is particularly serious, and along with the increase of concentration of indoor formaldehyde, asthma attacks and the risk of gradually increased between the two have a certain dose-response relationship, but only when the indoor formaldehyde reached a certain high level of concentration, the risk of asthma will not be felt, thus avoiding excessive indoor decoration, passive smoking, reduce indoor pollution levels and ultimately achieve the purpose of the protection of children's health.
Keywords/Search Tags:formaldehyde, decorated houses, asthma, children, indoor air pollution, risk factor
PDF Full Text Request
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