Analysis Of Impact Factors On Duration Of ICU Of Severe Sepsis And Septic Shock

ObjectiveTo determine the relationship between PaO₂/FiO₂.APACHE-â…¡score.Serum Lactate.duration of ventilatory support.incidence of DIC.incidence of MODS and the duration of ICU,to find the risk factor which can influence the duration of ICU,and apply it to the clinic medicine to shorten the duration of ICU.MethodsWe studied 51 septic patients after abdominal operation who were admitted to ICU between June 2006 and September 2007.Patients were divided into short and long group according to the duration of ICU.Datas were collected as following: PaO₂/FiO₂.APACHE-â…¡score.Serum Lactate.duration of ventilatory support.incidence of DIC.incidence of MODS and the duration of hospitalization.Values were presented as mean±standard deviation(x±s),statistical analysis of the data was accomplished by using student's t test and x² analysis.A statistically significant difference was indicated by a P value(P＜0.05).ResultThere was significant difference in PaO₂/FiO₂.APACHE-â…¡score.Serum Lactate. the incidence of DIC.the duration of ventilatory support.the,duration of hospitalization and the incidence of MODS between the two groups patients.Patients with over 48 hours duration of ICU had significant longer time than did those less than 48 hours(P＜0.01).And they had higher incidence of MODS. Conclusion1.This study supports the concept that PaO2/FiO2.APACHE-â…¡score.Serum Lactate. the duration of ventilatory support,can influence the duration of ICU when the patients with abdominal operation were adimitted to ICU.They are the reliable predictors of the duration of ICU.2.We must provide aggressive therapy for the patients who will stay in ICU for more than 48 hours,maybe which is the key to reduce the mortality of MODS.