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The Clinical Analysis Of 106 Female Patients With Congenital Genital Malformation

Posted on:2009-04-21Degree:MasterType:Thesis
Country:ChinaCandidate:Y L LongFull Text:PDF
GTID:2144360242981315Subject:Clinical Medicine
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Object: To investigate the clinical character and therapy of female congenital genital tract malformation.Methods: Retrospectively analyze patients of genital tract malformation that accepted at the first hospital of Jilin university during the period of 1988-2007.Results: There were 106 patients of genital tract malformation,in which there were 15 cases of imperforate hymen, 11 cases of vaginal atresia, 34 cases of congenital absence of the vaginal, 14 cases of vaginal septum, 17 cases of double uterus and 19 cases of uterine septum. There was 1 case of transverse vaginal septum complicated with double uterus, 1 case of longitudinal vaginal septum complicated with longitudinal uterine septum, 2 cases of oblique vaginal septum complicated with double uterus. There were 4 cases which involving urinary system, in which there were 3 cases double uterus complicated with congenital absence of left kidney, 1 case vaginal atresia complicated with dysplasia of right kidney. The congenital heart disease was involved in the patient with MRKH syndrome. The sickness rate of genital tract malformation was 4‰. The sickness rate of different period is different, they were 3.27‰during 1992~1996, 2.53‰during 1997~2001, 5.27‰during 2002~2007.10. Statistics the difference under the three period ,χ2=8.95,P<0.05. The constituent ratio of imperforate hymen was 11.1% (11/99), vaginal atresia was 8.1% (8/99); vaginal septum was 12.1% (12/99); congenital absence of vaginal was 32.3% (32/99); double uterus was 17.1% (17/99); uterine septum was 19.2% (19/99). The sickness rate of imperforate hymen was 0.5‰(11/23733); vaginal atresia was 0.3‰(8/23733); vaginal septum was 0.5‰(12/23733); congenital absence of vaginal was 1.3‰ (32/23733); double uterus was 0.7‰(17/23733); uterine septum was 0.8‰(19/23733). The clinical manifestation mainly include primary amenorrhea (34 cases,30.9%); cyclical lower abdominal pain (32 cases,29.1%); difficulty intercourse (5 cases,4.5%); large vaginal bleeding after intercourse (2 cases,1.8%); abortion (30 cases,27.3%); sterility (7 cases, 6.4%). The patients with imperforate hymen were diagnosed at 11~18 years old,vaginal atresia were diagnosed at 13~20 years old,vaginal septum were diagnosed at 12~28 years old ,the congenital absence of vaginal were diagnosed 16~32 years old,didelphys were diagnosed 24~51 years old. The septum utetus patients were admitted at 22~38 years old .The length of staying in the hospital: imperforate hymen was 2~18d, mean was 6d; vaginal atresia was 4~14d, mean was 7d; the time of congenital absence of vaginal different by defferent therapy. Frank's method was 3~6d, mean was 4.5d, vaginoplasty by transabdominal-vulvar suspensory model was 24d, ileal vaginoplasty was 14~35d, mean was 20.5d; vaginal septum was 4~15d, mean was 7d; didelphys was 4~23d, mean was 9.6d; uterine septum was 4~11d, mean was 6d. The time of staying in the hospital of congenital absence of vaginal was longer than other kinds of malformation, P<0.05. The staying time was shortening these years such as ileal vafinoplasty for patients with congenital absence of vaginal. And the mean time was 24 days during 1988 to 1995, 22 days during 1996 to 2000, 17 days during 2001 to2007. The mean staying time of uterine septum was 7 days during 2001 to 2003, 5 days during 2004 to 2007. After the appropriate therapy, the clinical symptoms of the patients were remittence and the physical need was satisfied.Conclusions:①The most common female congenital genital malformation was congenital absence of vaginal ,and next was uterine septum.②The sickness rate of all kinds of genital malformation was 4‰,which is a little high.③With the development and elevation of operation technique for genital malformation, the effect has been elevating and the time staying in the hospital has been decurtating ,the patients feel satisfied .
Keywords/Search Tags:congenital, genital tract malformation, MRKH
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