Evaluation Of The Simple Methods In The Diagnosis Of Diabetic Peripheral Neuropathy

Objective To evaluate the clinical usefulness of graduated 10g monofilament exam,thermal sensibility,vibrayory sensation in the diagnosis of diabetes peripheral neuropathy·Methods The clinical data of 95 patients with type 1 diabetes,type 2 diabetes or impaired glucose tolerance (IGT) (according to the criteria of WHO)and without cerebral vascular,lumbar vertebra disorders and cognitive disorder。10 g monofilament examinations,thermal sensibility,vibrayory sensation,electrophy- siological examination were carried out in all the patients . Using the results of NSV as golden criteria , the sensitivity , specificity , positive and negative predictive values and kappa values of these tests including parallel tests were analyzed . Results The the sensitivity of the seven test(10 g monofilament examinations,thermal sensibility,vibrayory sensation,the parallel test of 10 g monofilament examinations and thermal sensibility,the parallel test of 10 g monofilament examinations and vibrayory sensation,the parallel test of thermal sensibility and vibrayory sensation,the parallel test of 10 g monofilament examinations,thermal sensibility and vibrayory sensation) are 16.2%,89.7%,61.8%,89.7%,63.2%,92.6%,92.6% respectively . specificity were 96.3%,40.7%,85.2%,40.7%,81.5%,33.3%,33.3% respectively. And kappa values were0.077,0.338,0.377,0.338,0.366,0.304,0.304 respectively .Conclusion 10 g monofilament examinations could not be perfect for screening DPN in early stage .Vibrayory sensation is a rapid , simple and reliable test for screening DPN. Uniting thermal sensibility test with 10 g monofilament examinations,vibrayory sensation can make a higher sensitivity.