Analysis Of The Clinical And Imaging Features Of Moyamoya Disease

Objective:To analyze the clinical and imaging features of moyamoya disease(MMD). To discuss the pathogenesy of MMD.Methods:45 patients with MMD who had been treated in the Anhui provincial hospital between 2000 and 2007 were included and their clinical and imaging data were retrospectively analyze in the study.Of them,17 patients were diagnosed by MRA, 26 by DSA and 2 by SCTA.Results45 patients ranging in age from 6 to 58 years old were analyzed.Of them,8 patients in the juvenile group(≤15years) and 37 patients in the adult group(＞15years).The peak incidence age was 40 years old and there were 20 patients ranging in age from 36 to 45 years old.19 patients were cerebral infarction and they were all multifocal cerebral infarction which could be found in the area supplied by internal carotid artery by CT or MRI.7 patients in the juvenile group were multifocal cerebral infarction and they all had cognition functional impairment.26 patients were hemorrhagic apoplexy.Of them,10 patients were cerebroventricular haemorrhage,9 basal ganglia haemorrhage,5 cerebral lobe haemorrhage,2 subarachnoid haemorrhage(SAH) and 25 fell ill in the adult. Abnormal vascular network in the vicinity of the arterial occlusion could be found in each patient pavimentum cerebri by brain angiography.Conclusion:MMD occurs more frequently in adult than children and teenagers.Children often have cognition functional impairment during the later period of the MMD. Hemorrhagic apoplexy frequently manifest cerebroventricular haemorrhage or basal ganglia haemorrhage.Multifocal cerebral infarction often could be found in the area supplied by internal carotid artery.The location of vascular lesions of MMD could be found by MRA,DSA or SCTA.Compared with MRA or SCTA,DSA more exactly show the stenosal blood vessel and the aneurysm.