Relationship Between The Mortality And The Levels Of Some Biochemical Indicators In The Acute Stage Patients With Hemorrhagic Stroke

ICH(intracerebral hemorrhage) is a kind of primary hemorrhage of the brain tissue,which occupies 20%~30% of the acute cerebral vascular accident.The annual incidence rate of ICH is about 60/100 thousands to 80/100 thousands and the mortality in the acute stage is approximately 30%~40%,which is the highest one of the acute cerebral vascular accident.In our country,along with the proceeding of the population aging,the amount of the people troubled by ICH increases year by year. Recently many doctors have found that some biochemical indicators often changed abnormally and the changes would indicate the prognosis to a certain extant. So if we can interfere in the risk factors reasonably while the effective therapy is given in time,the mortality and mutilation rate will degrade.Objective:To assess the mortality rate of the patients with different levels of BUN,UA,TG,TC,ALB,K+,Na+.Methods:We studied 683 patients with ICH retrospectively. The information we have recorded included name,sex,age,exact location of hemorrhage,if the patients had been diabetes or hypertension and the BUN,UA,TG,TC,K+,Na+,ALB on the first day or in the morning of the second day.Results:1.The mortality rate of the group with higher BUN was higher than the one with normal BUN(χ2=9.817,p=0.002)and with lower BUN(χ2=8.858,p=0.003).2.The mortality of the group with higher UA was higher than that of the patients with normal UA(χ2=9.914, p=0.002).3.The mortality of the group with lower TG was higher than that of the patients with normol TG(χ2=6.687, p=0.010).4.There was no difference among the mortality of the 3 groups with different levels of TC(χ2=4.887, p=0.087).5.There was no difference among the mortality of the 3 groups with different levels of ALB(χ2=1.260, p=0.532).6.The mortality of the group with higher Na+(χ2=31.525,p=0.000)and with lower(χ2=17.302,p=0.000)were higher than that of the group with normal Na+(χ2=1.004,p=0.199).7. There was significant difference among the mortality of the 3 groups with different levels of K+(p=0.029).Conclusions:1.The mortality of the patients with higher BUN in the acute stage is higher.2.The mortality of the patients with lower UA in the acute stage is higher.3.The mortality of the patients with higher or lower Na+ in the acute stage is higher.4.The mortality of the patients with lower TG in the acute stage is higher.5.The mortality of the patients with higher K+ in the acute stage is higher.6.Although there was no difference among the mortality of the groups with different levels of ALB or TC, we can not conclude that ALB or TC have no influence on the mortality. In order to identify the relationship between biochemical indicators and prognosis,long-term study with larger amount of cases needs to be carried out.