Clinical Research On Multiple Factor Intervention Of Improving The Insulin Resistance

Objective: Observe the effect of the QiHuang capsule which cure the type 2 diabetes patients and improve the insulin resistance. Methods: The all selected 120 patients were random divided into 4 groups ,the all 4 groups have the same base treatment, group A is simply interfere in life-style;the group B add the diformin;the group C add berberine;the group D add the QiHuang capsule with berberin.3 months later, observe the level change of FPG,2hPG,insulin,HbA1C,blood fat and the traditional Chinese medicine symptom and calculate the insulin sensitive index and insulin resistance index , compare the effect of all groups improving the insulin resistance. Results: Though 3 months treatment ,the FPG,2hPG,IRI level in group D patient was decreased in different degree and increase in IAI. Compare to the non-treatment, the difference is significant (p<0.05).After treatment, the FPG,2hPG,IRI level difference in the each group is also significan(tp<0.05).Conclusion: In cure the type 2 diabetes patient, add the QiHuang capsule with berberine conjunction the life-style interfere is not only derice in significantly improve insulin resistance, regulate the blood glucose ,the blood insulin and lipids level in body, but also having great safety in clinical use because which haven't significant side effect. Besides, in collecting the data, also found the short-term high glucose food and ageing is the main remote cause in the type 2 diabetes.