Objectives:To Investigate immune function,nutritional status,function of liver and kidney,bowel function effect of early enteral nutrition in surgical patients with gastric cancer.Methods:Sixty patients were obtained from gastric cancer in 2006.and randomly divided into EEN group and PN group.The patients in EEN group received Fresubin early enteral nutrition from postoperative day 1 to postoperative day 7.The patients in PN group received total parental nutrition.IgA,IgG,IgM,CD3~+,CD4~+,CD8~+, CD4~+/CD8~+,ALB,PA,PF,UCB,CB,ALT,AST,CREAT,BUN were detected on the day before the operation and the postoperative days 1 and 8.And the restoring time of intestinal movement was observed.Results:(1)As compared with the day before the operation,all the levels of IgA,IgG,IgM,CD3~+,CD4~+ and CD4~+/CD8~+ in two groups were decreased on the 1 day postoperatively.However,the changes in the EN group was significantly different from PN group on the 8 day postoperatively(P<0.05).(2)On the 1 day postoperatively,ALB,PA,TF in tow groups decreased significantly(P<0.05,P<0.05, P<0.01).On the 8th day,there were no significant differentce in ALB,PA,PF in EN-group than in PN-group(P>0.05).(3)No significant differences existed between these two groups in UCB,CB,ALT,AST,CREAT,BUN before operation and on the 1,8day postoperatively(P>0.05).(4)The restoring time of bowel movement was significantly decreased in the EN group compared with PN group after operation(P<0.01).In both EEN group and PN group there were no serious complications.Conclusions:Early enteral nutrition can improve nutritional status,and compared with the parenteral nutrition, EEN can enhance obviousely immune function and promote the recovery of bowel function in gastric cancer surgical patients.
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