Evaluation Of Acute Cerebral Infarction With Somatosensory Evoked Potentials And Brainstem Auditory Evoked Potentials

ObjectiveThe aims of this study were to explore the value of application median nerve short latency somatosensory evoked potentials and brainstem auditory evoked potentials to diagnose the patients of acute cerebral infarction with negative intracranial CT, to investget the value of BAEP in monitoring hemispheric infarction, and to compare the prognosis of the patients with different SLSEP grading.Methods62 patients with acute cerebral infarction were collected from August 2005 to November 2006 in departerment of neurology of the first affiliated hospital of soochow university, some of the patients were rechecked by intracranial CT or MRI late, and calculated infarction volume. All were checked by SLSEP and BAEP within 72 hours of admission, part of them were rechecked on the basis of condition. All patients were scored by Chinese Stroke Scale within 72 hours of admission, and rescored after a month.Results1.Compared with single application of SLSEP, association of SLSEP with BAEP could elevate diagnostic rate of patients of acute cerebral infarction with negative intracranial CT, but they were not statistical significant(P>0.05).2.Abnormal rate of SLSEP was different in diverse locus of brain, the lobe of brain is the highest in all. Amplitude of N20 wave was low or disappeared when apical lobe was infarcted. When the patients have deep sensory disability or aphasia, abnormal rate of SLSEP was 100%(25/25,10/10). Compared with the patients without deep sensory disability or aphasia, the abnormal rate of SLSEP was statistical significant(P<0.01).3.BAEP change was reflected in hemispheric infarction, abnormal rate of BAEP was increased along with increasing of the volume of infarction. Abnormal rate of BAEP was 100%(10/10), when the volume of infarction exceeding 30ml. Abnormal rate of BAEP was 0(0/20), when the volume of infarction was lower than 10ml.4.The prognosis of patients with different abnormal levels of SLSEP was different, it was worse along with higher abnormal levels of SLSEP.Conclusion1.Median nerve short latency somatosensory evoked potentials had aided diagnostic valuation on the patients of acute cerebral infarction with negative intracranial CT, associated application of SLSEP and BAEP was not better than single application of SLSEP.2.Abnormal rate of SLSEP was different in diverse locus of brain, the lobe of brain is the highest in all. Amplitude of N20 wave was low or disappeared when apical lobe was infarcted., Abnormal rate of SLSEP was 100%, when the patients had deep sensory disability or aphasia.3.BAEP grading and its dynamic changes could monitor the function of hemispheric infarction.4.The prognosis of patients with different abnormal levels of SLSEP was different, it was worse along with higher abnormal levels of SLSEP.