An Initial Study Of Accuracy Of 64-slice CT For Detecting Coronary Artery Stenoses

ObjectiveTo evaluate the diagnositic accuracy for the the assessment of coronaryartery stenoses with 64- slice computed tomography (CT) scanner.Methods64- slice CT angiography was performed in 29 patients(23 male, 6female; mean age 61.2±5.3 years) with known or suspected coronary arterydisease(CAD) and compared selective coronary artery angiography (SCA).The rhythm of all the patients was stable sinus. Patients with initial heartrate≥90 bpm receivedβ-blockers. All available coronary segments (≥2.0mm) were included in the evaluation. Lesions with≥50 luminal narrowingwere considered significant stenoses. Evaluations had been done concerningthe 64- slice CT scanner for detecting the stenosis of the variant branches orsengments of the coronary artery. According to the nature of motion artifactsand image evaluation for stenosis, image quality was rankedⅠ～Ⅳ.ResultsNone of the coronary segments (n=386) needed to be excluded from analysis. SCA was used as the golden standard, Overall sensitivity forclassifying stenoses was 88%(126/143; 95% CI:82-94), specificity was 92%(224/243; 95% CI: 89-96), positive predictive value was 87% (126/145;95% CI: 82-93), and negative predictive value was 93% (224/241; 95% CI:88-99). Arterial wall calcification was the main influence factor for accuracyof the the assessment of coronary artery stenosis with 64-slice CT scanner.Conclusion64-slice CT scanner provides a high diagnostic accuracy in assessingstenoses of the coronary artery.