ObjectiveTo assess the reliability, feasibility and superiority of Osteo Set artificial bone and autogenic bone grafting combined with internal fixation after radical debridement in the treatment of spinal tuberculosis.MethodsA before-after study was in different group patients. Experimental group: 20 cases, radical debridement, OsteoSet artificial bone and autogeneic bone grafting combined with internal fixation; control group: 20 cases, radical debridement, bone autograft combined with intemal fixation. Radiographs (X-rays and CT scans) were analyzed before operation, immediately after operation, 3 months, 6 months and 12 months after operation to access bony fusion and deformity correction.ResultThe average in-patient days was 19.5d (12-27d.). All the patients acquired satisfactory incision healing without fever. The average WBC account one week after operation was 8.2×10~9. The follow-up period ranged from 12 to 48 months (mean 26 months). There was no recurrence of the disease or loose instrument. The average cobb's angle corrected was 15°. The rate of fusion in experimental group was 40%(8/20) in 3 month after operation, and was 85% (17/20) in 6 month after operation. While in control group it was 10% (2/20) in 3 month after operation and 55% (11/20) in 6 month after operation.ConclusionOsteoSet artificial bone can avoid the complications of donor bone site, and achieve bony fusion earlier than using autogeneic bone alone. The early clinical outcome is satisfying.
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