A Follow-Up Study: The Maternal And Infant's Iron Status

PART ONEMATERNAL IRON STATUS AND NEWBORN'S IRON STATUS【Objective】To investigate the iron levels of the pregnant women and the neonates, explore the relationship of the iron status between the mather and the newborn, analyze the factors influencing the iron status in the neonates.【Methods】127 pairs of the pregnant women and neonats were followed from the second trimester to delivery during the period from March 2006 to October, 2006.The blood samples of the maternal venous and the umbilical cord were collected at the second and third trimester, and at the delivery,respectively, the samples were analyzed for Hb,MCV,RDW at the same time.The CRP levels was measured to rule out the inflammation. The values of SF in the cord were compared with the indexes of iron status in the mothers.【Results】1. The prevalence of ID in the mothers at the 2nd and 3rd trimester and in the newborns'cord was 29.92%,39.37%,33.07% respectively. The prevalence of ID in the newborns born to the mothers with ID was higher than that in the neonats born to the health mothers.Almost 2/5 of the women were diagnosed as ID before the delivery.2.While the mother were demonstrated as ID during pregnancy, the values of SF in the cord blood were decreased significantly (P<0.05);The SF levels in cord blood born to the mothers with IDA at the second trimester were lower than that born to the mathers were LID (P<0.05) . 3.The results from multiple linear regression analysis showed that the SF values of the the pregnant women and the parity were the most important factors related with the neonatal iron store. 4. The results from logistic regression analysis showed that SF<20μg/L of the mother was one of the risk factors (OR=3.9876), and the maternal education levels and the family incomes were the protective factors (OR=0.1733)【Conclusions】1.There was positive relationship of the SF levels between mothers and newborns. The iron status of the newborns was affected by mothers with the mild ID during the pregnancy.2. The fetus iron store was affected by the maternal para,education levels and family incomes.3.The health care during pregnacy should be done according to the nutritional status of the mother. PART TWOA FOLLOW-UP STUDY : THE INFLUENTIAL FACTORS RELATED IRON STATUS IN INFANTS【Objective】To investigate the iron levels of the pregnant women and the infants,demonstrate the relationship of the iron status between the moher and infant,survey the crucial factors of the iron status on the infants.【Methods】1.100 couples of mother-baby were followed till the babys were 3~5 monthes old in the Department of Primary Child Care, Children's Hospital , ChongQing Medical University from October 2006 to February 2007 . The anthropometric measurements were studied during the visiting by two professional staffs. The assessments of growth were done by used CDC2000 reference . The blood samples of the infants were collected at the end of the fllow-up visits for analysis of Hb , RDW. ,sTfR.The values of sTfR of the intant were compared with the indexes of iron status in the mothers.【Results】1.39 cases were diagnosed as ID.Among them 36 cases(36/39,92.31%) were born to the mother with ID during pregnacy. 26 couples of mother-infant were normal during the following study.The prevalence of ID in the babys while the indexes of iron status were indicated as ID during the pregnancy and newborn was higher. 2.The sTfR values of the infants born to the mother with ID during pregnancy were decreased significantly (P<0.05). The SF values of the umbilical blood were negative correlated with the sTfR values of the infant(r=-0.8452, P<0.01).3.The prevalence of ID in the infants with△WAZ >-0.67 was higher obviasly than that in the infants with -0.67≤△WAZ≤0.67 (P<0.01). 4.There were no significant difference of iron status between boys and girls,and the iron status of the babys were not affected by the feeding patterns. 5.The results from multiple linear regression analysis showed that the SF levels in the cord blood and△WAZ of infant were the most important factors related with babys'iron status, the iron status of the babys were affected by the maternal SF levels.6.The results from logistic regression analysis showed that the SF<100μg/L in the newborns was one of the risk factors (OR=4.0256), and the maternal education levels and the family income were the protective factors (OR=0.3334)【Conclusions】1.The anemia of the infants aged 3~5 monthes were correlated with the iron shortaga during the fetus.2.The iron status of the baby were related with the gains in the weigh.3. The iron status of the infants aged 3~5 monthes were not affected by the sex and feeding patterns...