The Observation And Evaluation Of The Clinical Results In The Treatment Of Myopia With Q-factor Guided Aspherical Ablation

Purpose: To investigate and evaluate the clinical results of Q-factor guided Aspherical LASIK in the treatment of myopia (or with myopic astigmatism) by comparison with traditional planoscan LASIK in the aspects of safety,stability and effectiveness.Methods: A retrospective study with self-control and comparison between 2 groups was carried out where 63 patients with myopia (or myopia with myopic astigmatism),122 eyes(4 received single-eye treatment while others bilateral) were divided into 2 groups: study group,31 patients , 60 eyes underwent LASIK with the Q-factor guided Zyoptix Aspheric algorithm; control group,32 patients,62 eyes with traditional planoscan LASIK. In both of the 2 groups patients were examined and treated under the regular clinical LASIK standards and guidance by one surgeon with the same set of Technolas 217z Excimer Laser. The basic information of the patients as well as the diameter of mesopic pupil and optic zone were recorded. Patients were examined at the point of pre-operation,post-operation 1 month and 3 months with their following results noted: UCVA(uncorrected visual acuity),refractive status(spherical,cylinder and axis ),MRSE(mean refractive spherical equivalent),BCVA(best corrected visual acuity),K-value, Q-factor, contrast sensitivity and aberrations. Preoperative and postoperative parameters and their changes in each group and between the 2 groups were compared as well as linear correlations between the parameters were studied.Resuts: There is significant difference between the 2 groups as for the pre-operation MRSE, mesopic pupil and optic zone diameter(P<0.05).The post-operation VA and MRSE show no significant differences between the 2 groups(P>0.05).Patients in the study group feels more satisfied with there visual quality, which is also approved by the advantage in the CSF examination outcome(sP<0.05),with less change in Q-factor noted with significant difference(P<0.05).No significant difference is found between the 2 groups as for the value of post-operational HoRMS and spherical RMS as well as their changes during the period.Conclusion: At 3 months the Zyoptix Aspherical Algorithm shows reliable safety and stable effectiveness in the treatment of myopia and myopic astigmatism. Compared with Planoscan Algorithm there is less change in Q-factor. Longer investigation and observation is needed for a long-term assessment.