The Study On The Processing Method Of Pulse Wave Signal And Clinical Experiments

Recently,the material life of people is getting richer more and more, the fashion of life and the structure of bite and sup has changed a lot. Simultaneously, the death ratio of kinds of diseases ascends greatly, among which heart and brain vascular disease is the main reason for people's death and are endangering human's health heavily. The death ratio of hypertension places first in all the heart and brain diseases, thus, hypertension is names as"immaterial killer"of human health!The incidence of hypertension in adult, which has reached about 11.88%, has been boosting in china recently. The number of hypertension has passed 100 million. There are many problems in Hypertension's diagnosis and treatment, such as three highness problem—high incidence, high recrudesce rate and high lameness rate, three lowness—low discover rate, low diagnosis rate and low cure rate. Hypertension's syndrome, such as heart disease for hypertension, apoplexy and miocardial infarction etc are endangering human heavily. The satisfying controlling rate of hypertension in our country is less than 5%! Therefore, experts indicate that we should attach greater importance to the prevention than the treatment of hypertension.However, all the current cardiovascular state monitoring technology is invasive and not easy to operate, and their high cost restrict potential suffers'in-time detection which can forecast the trend of cardiovascular diseases'occurance. Therefore, seeking one safe, accurate, convenient and economical monitoring algorithm has become one important task in urgent affairs.This paper mainly involved six aspects work as follows:①Study the oscillometric method, the Windkessel theory and the pulse wave's transmission theory according to collected academic information,②Design the hardware project as a whole for the measurement instrument of vascular rigidity.③In the aspect of measuring pulse wave velocity, we summarized its normal noninvasive methods and their characteristics, on the base of which we propose a new method—double-cuff method, which has the advantages of simplicity, convenience and high speed. Clinical result indicates that the double-cuff method can measure pulse wave velocity accurately and reliably.④Before measuring arterial compliance, we studied its academic foundation and introduced its normal method-- plane pressure wave method and pressure oscillometric analysis method, on the base of which we proposed pressure curve imitation method and apply it to measure arterial compliance in clinical tests. Clinical result indicates that this method's accuration and reliability.⑤We code the software system on the software plane LABView and has completed its real-time communication, pulse wave signal's pre-treatment, the haemodynamics parameters'analyse and calculation, the results'saving and printing, etc.⑥Additionally, we have arranged clinical tests and analysed the data by group by the software Statistics Processing of Social Science (SPSS) to validate and improve the algorithm.