Clinical Research On The Relationship Between Syndrome Of Traditional Chinese Medicine Of Acute Myocardial Infarction And Degree Of Pathologic Changes Of Coronary Artery

Objective: we begin to our clinical study from Syndromes.We analyzed the peculiar-ity and the influential factors of the syndromes of AMI. Then we study the relationbetween the syndromes of AMI and the degree of pathologic changes of the coronaryartery so as to explore the pathogenesis of AMI and the train of thoughts to preventand cure it.Meathods:(1)The objects of research are 222 patients with AMI who have beenexamined by coronary angiography at the Heart Center of Guangdong Hospital ofTCM. (2)We finish the collections of syndromes of TCM and history-taking within 48hours ambi-CAG which has been done by standard technology. And we finish allkinds of related examination of laboratory within one week before or after CAG..Thenwe can obtain the diagnosis of western medicine and syndromes of TCM according tothe related criteria, so we finish the unified table of every clinical record of investigation.(3) Statistical method:USE the Statistical software of spss 13.0 for windows,weset up the database and analyze the data.Results:(1)The number of male patients is more than female,and at the age ofmorbility, male is earlier than female(P＜0.05).(2) Distribution of syndromes:Thestatistical analysis shows that the most common complex syndrome of the 222patients with AMI are the syndrome of the deficiency-syndrome of qi and thesyndrome of blood stasis and sputum-turbid(64.9％of total).The most commonsyndrom of excess and/or deficiency syndrom is the syndrom of combinant of excess and deficiency(200 cases 90％of total). The most comman simple syndrome ofthe 222 patients is the blood stasis ,and next is the syndrom of sputum-turbid,and nextis the diciciency-syndrom of qi,and next is the deficiency-syndrome of yin,and next isthe diciciency-syndrom of yang,at last is the stagnation syndrom of qi,and theaccumulation-syndrome of pathogenic cold is not found. (3)Results of CAG:82patients are single vessel disease (36.9％of total),and 72 cases are double vesselsdisease(32.4％of total),and 68 patients are triple vessels disease(30.6％of total).Thereare 82 patients whose target vessel are 100％of stenosis(36.9％of total), 90％-99％ofstenosis are 72 cases(32.4％of total),from 70％To 89％of stenosis is 28(12.6％oftotal),50％-69％of stenosis is 12(5.4％of total),below 50％of stenosis is 28 casestoo((12.6％of total).(4)Analysis of relationship between the syndrom of TCM and thecoronary artery disease: the syndrom of sputum-turbid is correlate to the number ofvessels of coronary disease(P＜0.05);the degree of the three simple syndroms,thedeficiency-syndrom of qi and the syndrom of sputum-turbid and the syndrom of bloodstasis are correlate to the degree of target vessel stenosis(P＜0.05);the compelxsyndrom is correlate to the number of the disease vessels.Conclusions:(1) Male is more than female with AMI,and age of morbidity is earliertoo.(2)The main combination syndrom of AMI is the syndrom of qi-deficiencysputum-turbid and blood stasis,the main simple syndrom is the syndrom of bloodstasis,followed is the syndrom of sputum-turbid,the deficienfy-syndrom of qi,thedeficiency-syndrom of yin,the deficiency-syndrom of yang,and the stagnate syndromof qi.so we think the treatment of AMI is to benefit qi and activate blood andeliminate sputum ,so that the blood circulation can be promoted. (3)More disesaevessels,more complex syndrom,and more the sputum-turbid syndrom.Aolne with theincreaseing degree of target vessel stenosis, the degrees of the syndrom of blood stasisand the syndrom of sputum-tuibid and the deficiency-syndrom of qi are raised.