The Difference Of Event-related Potential Between ADHD And Healthy Children

Objective: To characterize the changes of ERP in children whosuffer from ADHD, so that we can find a objective way to diagnose ADHD. Method:Twenty-one patients of ADHD and nineteen healthy volunteers whose age and gender ismatched with the group of ADHD received the examination of ERP. All subjects weredemanded to press left or right button as quickly as possible while stimulus materialthat were a serial of round figures were randomly presented in the center of screen. Ifthe colors of two round compared were identical, we looked them as match condition,and the colors of two round compared were different, we looked them as mismatchcondition. Both conditions were of equal probability. Result: Under the matchcondition, P₁₀₀,N₁₉₀,P₃₀₀ could be elicited, and under the mismatch condition, N₂₇₀could be elicited. 1 The mean amplitude of P₁₀₀ elicited after treating in ADHD groupwas more positive than those elicited in control group in the second time. The latencyof P₁₀₀ was longer in ADHD group than in control group. 2 The mean amplitude ofN₁₉₀ was more positive in second time than in first time in both groups. At the sametime the latency of N₁₉₀ became longer after treating. 3 The mean amplitude of P₃₀₀was more positive after treating. 4 The mean amplitudes of N₂₇₀ became more positiveafter treating. And the latency of N₂₇₀ was longer in ADHD group than those incontrol group. Conclusion: Because the cognition of children who suffer from ADHDwas damaged, the ERP that represents the process of cognition also become differentfrom normal. Among all of the waves listing above, the N₂₇₀ is more sensitive.