A Surveillance Study On Bacterial Distribution And Resistance In Patients With Lower Respiratory Infection

Objective: To study the distributive characteristics, antimicrobial sensitivity and antimicrobial resistance of strains isolated from patients with lower respiratory infection.Methods: From 2004 to 2006,410 clinical isolates were acquired from phlegm specimens and bacterial susceptibility test was carried out by Kirby-Bauer method according to NCCLS standards.Result: Gram-negative rod was 68.05%. Pseudomonas aerations,Klebsiella,Escherichia coli,baumanii,Haemophilus influenzae,Entembacter cloacae were in the first place. Gram-positive cocci was 31.95%. Pathogenic streptocoui,Staphylococcus aureus,Streptococcus pneumoniae were in the first place.The most active agents against Gram negative organisms were Tienam,Cefepime dihydrochloride,Kanamycin and Pipeacilline/Tazobac. Gram-positive coccis were senstitive to Vancomycin,Piperacillin,Piperacillin/tazobactam.Conclusion: Pathogens of patients with lower respiratory infection are mainly Gram negative organisms and they are multidrug-resistance;it is essential to pay more attention to the Continuous surveillance of antimicrobial resistance in clinics and prevent transmission and epidemic of their resistance strains, It is very important to select antibiotics for the treatment of infection rationally.