Effects And Mechanisms Of Biqing Capsule On Curing Hyperuricemia

Purpose: It is to explore the function of BiQing capsule on Hyperuricemia and search for the mechanism of the action entatively.Method: Preventive for in medicine foundation, the mouse abdominal cavity injection Hypoxanthine creates the Hyperuricemia model, after the color method measured makes to order the mold 1h, 2h, the 3h mouse blood uric acid level, the observation BiQing capsule to the Hyperuricemia preventive treatment function; For the hundred daysage egg chicken oral administration high protein high calcium feed establishment endurance Hyperuricemia animal model, After that gives the BiQing capsule to fill the stomach two weeks, after for the medicine in front of and for the medicine two weeks, extracts the chicken wing varicosity , takes the blood serum determination blood uric acid, the blood urea nitrogen (BUN), the creatinine (CRE), the content and xanthine oxidase activeness (XOD), observation BiQing capsule to various targets influence; The use biology microscope observation mouse for the medicine around the auricle micro circulation blood vessel thin artery, the thin veincaliber, the blood capillary opens the quantity, the blood stream speed change, the observation BiQing capsule invigorates the blood to remove extravasated blood to affect。Result: The BiQing capsule may suppress the mouse temporary blooduric acid which large dose abdominal cavity injection Huang Piaorecites creates to elevate; Can reduce the Hyperuricemia modelchicken's blood uric acid level, the increase excrement uric acidcontent, suppresses the XOD vigor, reduces CRE, the BUN content; May cause the normal mouse auricle thin artery and the thin varicosity caliberin creases, the blood stream speed speeds up, the filamental flow, aline grain of class obviously increases, the auricle blood capillaryopen quantity increases.Conclusion: The BiQing capsule may effectively reduce the Hyperuricemia animal model blood serum uric acid level, has the suppression model kidney damage the function. Its function possibly through suppresses in vivo XOD activeness to suppress the uric ogenesis, the promotion uric acid excretion realization.