Early Diagnostic Value Of Plasma And Urine Concentration Of Intestinal Fatty Acid Binding Protein In Stomach Intestine Failure In The Critical Children

Objective Study the early diagnostic value of plasma and urine concentration of Intestinal fatty acid binding protein in stomach intestine failure in the critical children.Method Forty-three patients with severe case, aged from 1 months to 14 years old were enrolled, and according to if have stomach intestine failure the patients were divided into two groups, no stomach intestine failure group(18 patients), stomach intestine failure group (25 patients). 30 age-matched normal children were as controls. Plasma and urine IFABP was measured using enzyme immunoassay.Results Plasma and urine IFABP concentration in stomach intestine failure was significantly higher than other groups. Plasma: There is no statistical significance between no failure group and normal controls (P >0.05), there is statistical significance between no failure group and failure group(P<0.05), there is statistical significance between failure group and normal controls (P<0.05) . Urine: There is statistical significance between no failure group and normal controls (P<0.05), there is statistical significance between no failure group and failure group (P <0.05), there is statistical significance between failure group and normal controls(P<0.05). Plasma IFABP was positively correlated with Urine IFABP, Peatson's coefficient correlation is 0.941 (P<0.0005).Conclusions Plasma and urine IFABP level could be used to early warning stomach intestine failure group of critical children...