The Multifactors-nonlinear Model Of The Process Of Blood Stasis Syndrome(BSS) Changing

Objective: To research the parameters of blood steam.hemorheology and ET,NOand the expressions of VCAM-1 ,ICAM-1,PECAM-1 within the process of blood stasis syndrome(BSS) changing to construct the multifactors-nonlinear formulas and then to explore the mechanism of blood stasis syndrome(BSS) changing.Methods: The rat models with BSS were made by injection of Adrnine(Adr) andputting into combination of ice and water.Rats were randomisized into nine equal geoups: one was the nomal group and other eight were the model groups.To research the parameters with hemorheology,radiation immunization method , spectrophotometric methods and immuohistochemistry and image analysis ,with the method of documents, to construct the multifactors-nonlinear formulas .Results:1. Using the parameters of hemorheology to construct the multifactors-nonlinear formula of changing of blood stasis syndrome(BSS)Y=580. 351-1734. 228/X₈+1403.386/X₁₀-1750.56/X₃-3364.2/X₁+3. 107 X₆-0.09 X(?)². The formula suggests that blood stasis degree(BSD) changes with power-function.2. Using the parameters of ET and NO to construct the multifactors-nonlinear formula of changing of blood stasis syndrome(BSS)Y=62.916-1408.26/X₁+93060.632X₂^-1.9096.The formula suggests that blood stasis degree(BSD) changes with power- function.3. Using the parameters of the expressions of VCAM-1, ICAM-1,PECAM-1 do not to construct the multifactors-nonlinear formula of changing of blood stasis syndrome(BSS).Conclusions:The BSS model can be established successfully;the multifactors-nonlinear formula of changing of blood stasis syndrome(BSS) can be established successfully;the multifactors-nonlinear formulae suggests that blood stasis degree(BSD) changes with power-function and BSS has an unique essence.