The Relationship Between Age And The Clinical Characteristics Of Bladder Carcinoma In Adult Patients

Objective To study the relationship between age and the clinical characteristics of bladder carcinoma in adult patientsMethods The clinical data of 144 adult patients with bladder carcinoma was retrospectively reviewed. According to their age, the patients were classified into 3 groups: <40 years group, 40-60 years group and >60 years group. The gender ratio, haematuria, clinical stages, pathological grades and appearanc, number, progression of the 3 groups were compared to determine the relationship between age and the clinical characteristics of bladder carcinoma in adult patients. Results The male/female ratio was 8.0:1.0 vs 4.4:1.0 vs 3.1:1.0 in <40 years group, 40-60 years group and >60 years group. There was no significant difference in the male/female ratio between the 3 groups. Haematuria also was the frequent symptom. The percentage of haematuria in <40 years group was lower than that in >60 years group, but there was no significant difference among 3 groups(P>0.05). The <40 years group had a higher percentage(22.2%) of incidental tumor compared with those in the other 2 groups, but no significant difference appeared when compared among them(P>0.05). At the factor of tumor numbers, the percentage of multiple tumors in 3 groups is: 11.1% vs 29.6% vs 46.9%. There was significant difference between the 3 groups (P=0.029). The percentage of invasive tumor increased with the increasing age (11.1% vs 44.4% vs 50.6%), but no significant difference appeared(P=0.076). There were significant differences when the pathologic grades were compared among the 3 groups(P=0.021). Conclusions There is close relationship between age and the clinical characteristics of bladder carcinoma in adult patients, which leads to different clinical features in different age groups. Those characteristics have significant meanings to treatment and prognosis.