Surgery For Stage â…¢ Non-small Cell Lung Cancer (NSCLC) A Meta-analysis Of Randomized Controlled Trials

Objectives: To assess whether surgical resection compared with, radiotherapy or chemotherapy or combined improves the five-years disease-specific and all-cause mortality in patients with stage III NSCLC.Methods: According to the Cochrane reviewer's handbook, included studies were those on patients with histologically confirmed local advanced non-small cell lung cancer (NSCLC). The search strategy was developed according to the Collaborative Review Group search strategy. Medline, CBM, Cochrane library, articles in the academic degree collections were searched for clinic trails comparing efficacy of local advanced NSCLC with or without surgical therapy. Trials of RCT would be assessed for quality according to the concealment of treatment allocation, blinding of patients and outcome assessors, adequate descriptions of numbers and reasons for patient withdrawl and graded their methodologic quality according to the method of Higgins. Data would be extracted from each identified paper independently...