Changes Of Expression Of Neuroglobin In Rats With Experimental Intracerebral Hemorrhage

Part One Establishment of intracerebral hemorrhage model in rats by injecting autologous bloodBackground The pathophysiological mechanisms of intracerebral hemorrhage (ICH) are not fully understood and there is still no effective way to treat the disease clinically. So, it's very meaningful and useful to establish a reproducible and reliable ICH model for studying the pathophysiology of ICH. Objective To establish a ICH model in rats by injecting autologous blood with double-injection method. Methods 66 rats were randomly divided into normal control group (n=6), sham-operated group(n=30) and ICH group (n=30) . Sham-operated group and ICH group were divided into 5 subgroups separately according to 1,6,24,48 and 72 h after the animal modal...