Comparison Of Drugs Used In Combined Spinal-epidural Analgesia For Labor Pain

Labor analgesia is not only a symbol of modern civilized obstetrics , but also a benefit which each parturients should share, and also labor analgesia can enhance the safty of both mother and child in labor. Further study on labor analgesia is one of important task in obstetric health. A large difference is present in the choice of medicines which are different in effects and duration for mother and fetus in labor analgesia. We are attempting to seek the more ideal compatibility and concentration of medicine.ObjectiveThe purpose of the study is to observe the efficiency and safety for labor pain using combined spinal-epidural analgesia with three drug on mother and fetus, and to find out the best compatibility and dosage of medicine to relief labor pain.Methods300 (ASA)â… -â…¡parturients with a singleton vertex pregnancy were randomized into three experiment group, including ropivacaine group (group R), sufentanil group(group S) and the group of ropivacaine plus fentanyl(group RF). Another 100 delivery woman without using any analgesics was chosen as control group. Analgesic effect on mother and newborn were observed and recorded .Results(1) Analgesic potency comparison. Good analgesic effects were obtained in all three analgesic groups. The onset of analgesia in group RF and group S was significantly faster than that in group R(P<0.01). There was no significant difference between group RF and group S (P>0.05).