Effect Of Extracorporeal Shock Wave On The Bone-implant Interface In Rabbits

Nowadays more and more prosthetic replacements have been performed, and the applying duration has been lengthened. Loosening of artificial joint without cement has been a commom problem in orthopedics surgery. This problem can not be solved satisfactorily except re-replacement. Every year about 100,000 cases of replacement operations were performed in our country. Those joints which were replaced one or two decades ago are facing re-replacement surgery with time going. If every re-replacement operation cost 40,000-60,000 yuan, and there are 5,000 cases of re-replacement operations in our country every year, the total cost is about 0.25 billion yuan. Can we re-stabilize the loosened artificial joint by some other extrinsic interventions, but not re-replacement? This is the original point of our experiment. It can not only release the pain of patients, but also relieve the financial burden of families and society. Extracorporeal shock wave(ESW) was applied in clinical medicine in 1980s to treat the renal calculus. Now it has been the priority treatment of renal calculus and urinary calculus. In 1985, people started to research the effects of ESW on bone. In 1987, a Hungarian scholar took the lead in applying ESW on patients with nonunioned fracture. Then he found that ESW could promote healing of fracture. From then on, more and more researchs showed that extracorporeal shock wave treatment(ESWT) could promote or induce bone formation by activating hyperplasy and differentiation of osseous cells between fracture fragments. Recently, the research target of ESW has turned to artificial joint re-replacement, osteochondrosis and tissue engineering. Some oversea scholars tried to use ESW in bone-cement interface before re-replacement of artificial joint with cement, and found that the bone cement could be pulled out easilier after ESWT. It is not reported that ESWT can re-stabilize the loosened artificial joint without cement or not. To study the effect of extracorporeal shock wave(ESW) on the bone-implant interface, we pereformed shocks on the bone-implant interface of Japanese rabbits with artificial shaft in the femurs, then tested biomechanically and observed by...