Relationships Between The Distribution Of Abdomianl Adipose Tissue And The Components Of Metabolic Syndrome And Cardiovascular Damage

Clinical studies show that cardiovascular risk factors,such as obesity,hypertension,hyperglycaemia and dyslipidemia are often assembled with in some patient.This was identified as metabolic syndrome(MS).The diagnostic criteria was suggested in the third report of the national cholesterol education program expert panel on detection,evaluation,and treatment of high blood cholesterol in adults(ATP-Ⅲ) final report in 2001.The prevalence of MS and its cardiovascular complication is incredibly increasing in the past decades,it's mainly due to the increase of obesity subjects,especially abdomen type obesity,in which the incidence rate of hypertension,hyperglycaemia and dyslipidemia is obviously increasing.Its primary feature is the accumulation of visceral adipose tissue in abdomen.Although it has recently been found the relationship of obesity and the other profiles of MS,cardiovascular complication,they were primary based on the simple parameter such as waist circumference,waist-to-hip ratio,body mass index,etc.The relationships between the distribution of abdominal adipose tissue and the profiles of MS,and its effect on the cardiovascular damage is rarely reported.This study aims to investigate the distribution of abdominal adipose tissue in subjects and its effect on cardiovascular damage to provide an opportunity to prevent or delay cardiovascular events in patients with obesity and MS.Subjects and Methods1. Subjectsfive hundred and fifty one patients aged 21-80 years old (male 301, and female 250) were divided into four groups.1) VA<60cm~2(118);2) 60≤VA<90cm~2(154);3) 90≤VA<125cm~2 (144);4) VA≥125cm~2(135).MS was diagnosed by modified NCEP-ATP III criteria in 2001.DM was defined according to the criteria of ADA in 1997.Hypertension was defined according to the criteria of WHO/ISH in 1999.