The Effect Of Laparoscopic Surgery On Human Phagocyte & RBC Immune Activities Of Patients With Benign Gynecologic Disorders

Objective:Although laparoscopic surgery has been widely accepted, little is known about its subjective clinical result of this less invasive. This study was designed to explore the effect of laparoscopic surgery on the host immune response in patients with benign gynecologic disorders required to operation. Alterations in peripheral blood leukocyte count, cytokine (interleukin-6 and tumor necrosis factor-α) levels in serum and red blood cell immune adhesive activities correlate with extent of tissue trauma and inflammatory reaction. By assaying the above parameters and recording patients'recovery situations during para-operative period, we evaluated differences in the systemic immune response and clinical outcome after laparoscopic and conventional surgical approaches (open surgery). Based on above findings, We try to provide further evidences for minimum incisions induced by the laparoscopic procedures.Methods: Data of sixty patients with benign gynecologic disorders required to surgery were collected from September 2004 to December 2005 in the Dept. of OB & GYN of second hospital of HeBei Medical University. According to treatment...