Discussion Of The Correlation Between Spiral CT Manifestation Of (T₄N_xM_x) NSCLC Patient And The Differentiation And Syndrome Grouping Of TCM

Objective: Observe the correlation between spiral CT manifestation of (T₄N_xM_x) NSCLC patient and the differentiation and syndrome grouping of TCM. Method: (T₄N_xM_x) NSCLC patients in the study were minutely evaluated the manifestations of spiral CT, clinical symptoms, and physical signs. Correct differentiation was given according to the criteria of differentiation grouping of Traditional Chinese Medicine (TCM) and syndrome grouping of TCM. SPSS 10. 0 statistical analysis software was used to observe the constituent ratio.Result: Totally 83 patients completed this study, and they are the inpatients from October, 2003 to January, 2006. As to the correlation between the spiral CT manifestations of (T₄N_xM_x) NSCLC patients and the differentiation grouping of TCM, the spiral CT manifestations of pulmonary carcinoma are mainly manifested as the invasion of trachea and malignant pleural fluid. Among the invasion of trachea and malignant pleural fluid problems, qi deficiency and phlegm-damp type is the most commonly seen differentiation of TCM, next are deficiency of both qi and yin, and qi stagnation and blood stasis. Among the invasion of trachea, type of qi deficiency and phlegm-damp is obviously more than the type of yin deficiency and interior heat, and flourishing of toxic heat, while the difference between them has statistical meaning (P<0. 05). As to the malignant pleural fluid, the type of qi deficiency and phlegm-damp is more than flourishing of toxic heat, and there is statistical meaning between them (P<0. 05). Among the type of qi deficiency and phlegm-damp, invasion of trachea and malignant pleural fluid are most commonly seen. Among the type of yin deficiency and interior heat, both qi and yin deficiency, and qi stagnation and blood stasis, malignant pleural occupies the most, and thereare statistical meaning (P<0. 05) while comparing with CT manifestations of other groups. As to the correlation between the spiral CT manifestations of (T4NXM,) NSCLC patients and the syndrome grouping of TCM, most of the spiral CT manifestations of pulmonary carcinoma T4 are invasion of trachea, invasion of blood vessel, hydropericardium, and malignant pleural fluid. Among the invasion of blood vessels, types of qi deficiency and phlegm-damp are commonly seen. Among the invasion of trachea, types of qi deficiency and phlegm-damp occupy a lot, and there is statistical meaning (P<0. 05) while comparing with the types of yin deficiency, phlegm heat, and qi stagnation. As to hydropericardium and malignant pleural fluid, types of qi deficiency, phlegm-damp, blood stasis, and yin deficiency are most seen. Among the types of qi deficiency, phlegm-damp, and phlegm-heat, most of them manifested as invasion of trachea and malignant pleural fluid, and there are statistical meaning (P<0.05) while comparing with the spiral CT manifestations of other groups. Among the types of yin deficiency and blood stasis, both of them showed malignant pleural fluid, and there is statistical meaning (P<0. 05) in the comparison with the spiral CT manifestations of other groups. As to the type of qi stagnation, malignant pleural fluid is commonly seen, and there is statistical meaning (P<0. 05) while comparing with the groups of vertebra invasion, blood vessel invasion, and hydropericardium, and the next is the invasion of trachea. Among the pathological types of pulmonary carcinomas, adenocarcinoma and squamous carcinoma are the most. As to adenocarcinoma, malignant pleural fluid is most commonly seen, and there is statistical meaning (P<0. 05) in the comparison of the spiral CT manifestations of other groups. As to squamous carcinoma, invasion of trachea and malignant pleural fluid are the most. As to the invasion of trachea, squamous carcinoma is obviously more than adenocarcinoma, and there is statistical meaning between them (P<0. 05). As to adenocarcinoma, most of the differentiation types of TCM are qi deficiency and phlegm-damp, qi stagnation and blood stasis, as well as yin deficiency and interior heat, and there is statistical meaning (P<0. 05) while comparing with the type of flourishing of toxic heat. As to squamous carcinoma, the type qi deficiency and phlegm-damp is most commonly seen, and there is statistical meaning (P<0. 05) in the comparison with other differentiation types of TCM. The next is the type of qi and yin deficiency. As to adenocarcinoma, most of the syndrome types of TCM are qi deficiency, yindeficiency, phlegm-damp, and blood stasis, and then is qi stagnation. As to squamous carcinoma, types of qi deficiency, phlegm-damp, and yin deficiency are most commonly seen. As to blood stasis type, adenocarcinoma is more than squamous carcinoma, and there is statistical meaning beweeen them (P<0. 05). Conclusion: 1. Among the (T4N,Mx) NSCLC patients of this study, most of the spiral CT manifestations of pulmonary carcinoma T4 are invasion of trachea and malignant pleural fluid. Most of the pathological types are adenocarcinoma and squamous carcinoma, and qi deficiency and phlegm-damp is the most of the syndrome grouping of TCM. Types of qi deficiency, phlegm-damp, and blood stasis are the most in the syndrome grouping of TCM, but the total constituent ratio has no statistical meaning. 2. Among the invasion of trachea and malignant pleural fluid, most of the differentiation type of TCM is qi deficiency and phlegm-damp, and the next is both qi and yin deficiency or qi stagnation and blood stasis. As to the type of qi deficiency and phlegm-damp, invasion of trachea and malignant pleural fluid are most commonly seen. Malignant pleural fluid could be seen in the types of yin deficiency and interior heat, both qi and yin deficiency, or qi stagnation and blood stasis, which is obviously more than the spiral CT manifestations of other groups. Among the invasion of trachea and malignant pleural fluid, qi deficiency and phlegm-damp are the most commonly seen syndrome differentiation of TCM. As to hydropericardium and malignant pleural fluid, the types of qi deficiency, phlegm-damp, blood stasis, and yin deficiency are frequently seen. Among the types of qi deficiency and phlegm-damp, invasion of trachea and malignant pleural fluid are commonly seen. Among the types of yin deficiency, qi stagnation, and blood stasis, malignant pleural fluid could be seen in all of them, and then is the invasion of trachea. As to the type of phlegm-heat, most of them are invasion of trachea and malignant pleural fluid. When the spiral CT manifested as invasion of trachea and blood vessels, most of the syndromes of TCM showed a series o deficiencies, and it was found to be "real excess and false deficiency syndrome" after the treatment. 3. The pathological types of pulmonary carcinoma are adenocarcinoma and squamous carcinoma. As to adenocarcinoma, malignant pleural fluid is most commonly seen. Among squamous carcinoma, most of them are shown as the invasion of trachea, and then malignant pleural fluid. As to adenocarcinoma, most of the differentiation types of TCM/j are qi deficiency and phlegm-damp, qi stagnation and blood stasis, as wellas yin deficiency and interior heat. As to squamous carcinoma, the type of qi deficiency and phlegm-damp is the most, and the next is both qi and yin deficiency. Among adenocarcinoma, most of the syndrome types of TCM are qi deficiency, yin deficiency, phlegm-damp, and blood stasis. As to squamous carcinoma, the types of qi deficiency, phlegm-damp, and yin deficiency are commonly seen. Among the type of blood stasis, adenocarcinoma is obviously more than squamous carcinoma.