| Bruguiera gymnorrhiza is a grove species of Rizophoraceae family. Histories of Folk medicine show this species is a medicinal plant that has efficacy in stringency, antidiarrhea, antimalaria, etc. Previous endeavors on fishing bioactive principles from this particular mangove plant have led to isolation of some structurally novel natural products such as cyclic disulfurs, oxygen-containing aromatic compounds, and diterpenes. In our recent study on bioactive compounds from this plant indigenous to Gurangxi, we isolated, by processes including extraction and partition with different organic solvents, isolation by colomn chromatography, and purification by chromatographic and or crystallizitional methods, 13 compounds. Spectroscopic data including IR, 1H-NMR, and 13C-NMR for all of them and MS and 2D-NMR such as 1H-1H-COSY, NOESY, HMQC and HMBC for some of them were established for their chemical structural elucidation. As a result from these endeavors, we identified 12 of them respectively as dioctadecyl (7R*, 8S*, E)-3-hydroxy-5, 5'-dimethoxy-8-3', 7-O-4'–neolign-7'-ene-9, 9'-dioate (1), ent-13, 16β, 17-trihydroxykaur-9(11)-en-19-oate(2), daucosterol (3), triacontanol (4), septadecanoic acid (5), beyeran-19-al-16-one (6), cholestol (7), stigmasterol (8), methyl 4-hydroxybenzoate (9), oleanolic acid (10), steviol (11), and methyl ent-16β, 17-dihydroxykaur-9(11)-en-19-oate (12), of which 1 belongs to neolignans, 2, 6, 11, and 12 to diterpenes, 3 to glycosides, 4 to long chain fatty alcohols, 5 to long chain fatty acids, 7 and 8 to sterols, 9 to aromactic compounds, and 10 to triterpenes. In addition, 13 were supposed to be 16,17-dihydro-17-O-13'-disteviol which needs more spectroscopic experiments and/or chemical experiments to support. |
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