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Study On Preparation And Properties Of Magnetic Bioactivity Glass-Ceramic

Posted on:2007-07-20Degree:MasterType:Thesis
Country:ChinaCandidate:W Z ZhangFull Text:PDF
GTID:2144360185494084Subject:Biomedical engineering
Abstract/Summary:PDF Full Text Request
A new way has been created for bone tissue since the inorganic bioactive materials were developed. Hydroxyapatite (HA),β-tricalcium phosphate (β-TCP) and SiO2-CaO-P2O5 system have been prepared and used in the bone repairing field. Apatite-wollastonite glass ceramic (AW GC) is composed of apatite and wollastonite phase which nominal composition is MgO-CaO-SiO2-P2O5. It has excellent biocompatibility and high mechanical properties. The study of magnetism shows that magnetic materials play an important role in some specific biomedical applications. Magnetic materials can markedly influence the functional state of living cells, and have high induction capacity for cell proliferation. Furthermore, the hyperthermia treatment for cancer using magnetic materials has been reported.The purpose of this work is to study a way that adding some rare earth in AW-GC to obtain magnetism in the traditional biomaterials which can get a better cell proliferation ability when used in the body. The application of the hyperthermia treatment for cancer of the magnetic materials is expected.Light rare earth (eg. Eu & La) was added to apatite-wollastonite bioactive glass-ceramic by sol-gel method. Then a novel bioactivity magnetic material, apatite/wollastonite magnetic glass-ceramic was synthesized. Porous AW MGC was prepared through pore-making process using steric acid as porogen, compression molding and sintering process. The phase compositions of AW MGC were characterized by X-ray diffraction (XRD) and the microstructure of it was characterized by scan electron microscopy (SEM). Its magnetization at normal temperature was measured by vibrating sample magnetometer (VSM). Its...
Keywords/Search Tags:bioactivity glass-ceramics, human liver cells, magnetic material, marrow stromai stem cells (MSC), rare earth
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