Study About The Effect And Mechanism Of Reduping Made From Traditional Chinese Medical Herbs Against Endotoxima Of Heat Stroke

BackgroudHeat stroke is an acute illness caused by the effect of heat during violent physical activity or working in the high temperature. It is divided into three types in which heat stroke is the most seriously that is one of the most familiar and frequently-occurring diseases in the exercises, military training and campaingn of southern parts of china in summer. In 2004, it was estimated incompletely that there were more than 50 persons died of heat stroke in Guangdong province. As a result, the prevention and cure of heat stroke is always focused highly by medical staffs because the disease damages seriously the human healthy and battle effectiveness of military, however, the pathophysiology mechanism of this disease is not clearly understood presently. Recently, it has been found endotoximia of intestinal plays a key role in the process of the disease. According to such theory, using drugs of anti-endotoxin may probably be have the effect positively to the treatment of heat stroke. Reduping, a novel endotoxin—antagonist made from traditional Chinese medical herbs, has the effect to destroy endotoxin directly outside the body and protect the mice attacked by endotoxin. At the same time, it also has the effects against bacteria and virus. It has been believed that the application of Reduping is to contribute to the treatment of heat stroke.