| Objective To evaluate the value of CT perfusion in the reflection of hemodynamic characters in local recurrences of rectal cancer and scar structures after operations. Materials and Methods 20 post-operative cases, with 13 men and 7 women, were performed with CT perfusion study. In 12 recurrence cases, two cases was re-operated, 3 was performed with colonoscopy. All five cases were proved by pathology. The other seven cases were proved by clinic according as renascent tumors in front of sacrum or focal thickened rectum, which increased as follow-up after more than three months or incorporated with increasing the level of CEA or metastasis. The former were seven cases. Eight cases were diagnosed as scars with follow-up. It take more than six months. The longest spend one year. Seven cases have no alteration and one case obviously became smaller. All cases were selected continuous four slices in which included the maximal lay of tumors and performed CT dynamic scans. All original datum were transmitted to the work station. BF and BV , of which the local recurrence, the scars and the normal muscles, were analyzed with commercial soft on the basis of non-deconvolve algorithm. MTT was gained by the formula(BF=BV/MTT). ALL data were analyzed statistically by paired t test and logistic regression. Results BF (29.59±6.62 ml·min-1·100g-1 )and BV(65.54±13.58 ml/100g)values of local recurrence were distinctly higher than others with statistically significance. There was no significance in MTT value(2.34±0.87s) between local recurrence and others. Compared with normal muscle, BF, BV and MTT value of scar had no statistical significance. BF and BV were independent prognostic factors, as the values of OR were 1.532 and 1.279. There was no statistically significance between MTT and local recurrences. Conclusion Multislice CT perfusion study enable to shows the difference of hemodynamics between local recurrence and scar structure. |
PDF Full Text Request