Biological Effects Of Apocynum Venetum Tea On Cardiovascular System And It's Safety Assessment

The Apocynum venetum is a natural herb belong to apocynaceae, mostly distributed in the northwest saline-alkali soil. The special growth environment makes it have many therapy and health functions. The Pharmacochemistry Studies enunciate that Apocynum venetum enrich of biological active compositions being good for cardiovascular system, such as total flavonoids, quercetin, water-soluble carbohydrate etc. Epidemical investigation discover the relations between low occurrence rates of cardiovascular diseases in the local people in Xingjiag region and the traditional practices of drinking Apocynum venetum tea over a long period of the time. A handful of crowds drinking Apocynum venetum tea feel discomfort in gastrointestinal tract, thus it's drinking safety have become the basis of development research. Our experimental research study the biological effects of Apocynum venetum tea on cardiovascular System, including it's blood pressure reduction function, serum lipids decreasing effects, Anti-aging effects, to provide a direct research basis for biological function development of Apocynum venetum. We also carry out toxicological evaluation of drinking safety on Apocynum venetum tea, taking expect to provide necessary safety basis for the medicine application of Apocynum venetum tea.The first part of this paper study the biological effects ofApocynum venetum tea on cardiovascular system.1. To investigate such health properties, hypertension animal model was made and short-term feeding studies were performed on model animal introducing Apocynum venetum tea (crude-leave-extraction) into daily diet. Experimental data showed the blood pressure of hypertension rats in the treatment group was significantly reduced with the status of no abnormal growth and no significant heart rate changing during 4 weeks experiment period. The above data indicate that the Apocynum venetum tea attributes to lowering high blood pressure health function in model animal thus owns its great potential to be used as natural hypertension...