| Objective: Experiment to study the different degree brain external injury an empress the density variety of the blood plasma ET-1 originally, study the ET-1 and the brain external injury severity degree with in the near future relation after prepare.Materials and methods: Choose to collect the vein blood 2 ml respectively the first day,the third day,the fifth day and the seventh day from September of 2005 to in January in 2006 a period brain external injury in my hospital to stay in the hospital a sufferer to add up to 48 examples in harm.Results: Experiment the result manifestation through this time, 2 sets of patient blood plasma content ET-1 inside the brain external injury sufferer's 24 h go up(P<0.05) all and obviously, and, heavy degree the set is obviously high after lightly win degree set(P<0.05), badly prognosis is obviously high good prognosis.(P<0.05)Conclusion: After harm 1 with in the week, the blood plasma ET-1 of two sets of sufferers all goes up gradually, the brain hurts the more heavy sufferer blood plasma density ET-1 more high.The blood plasma ET-1 participates the pathology in the brain external injury development process, and the blood plasma level ET-1 go up the range and the brain external injury to hurt the degree,course of illness development and prognosis in the near future closely related behind.
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