Investigation Of Severe Burn With Inhalation Injury In Clinical Therapy (76 Cases)

Objective:Severe burn with severity inhalation injury is importment cause of patientswith burn and focal point topic in investigation of clinical and basic intointernal and international. Cases of severe burn with severity inhalation injuryin past 10 years in our hospital were retrospective analysised in order toimprove the treatment level and develop experiences and therapeuticpathway.Data and methods:76 cases of burn surface area exceeding 50% with severity inhalation injurywere collected from 1993.1 to 2002.12 in Burn Department of NanFanghospital. We retrospective summarize earily resuscitation and occasion oftracheotomy and depth wound surface dermatoplasty. These data wereprocessed by SPSS 10.0 with Chi-square and independent sample t test.Result:1 .Patients of inhalation injury caused in flame burn and liquefied gas accountfor 8 5.5 % in total cases.2. Total amount of fluid replacement in first 24 hour of patients with inhalation injury salience beyond to the amount of calculation according formula. Total amount of fluid replacement in second 24 hour compares to the amount of calculation according formula have no difference and also to the crystal and water ( P>0.05), the colloid have difference compared with the amount of calculation according formula ( P=0.024). Average urine volume beyond to routine volume after burn 48 hours.3. Mortality of patients which have tracheotomy within 6 hours on severeburn with severity inhalation injury decreased compared with after 6 hours.(P=0.005)4. Mortality of patients which have excision escharsion within 4 days on severe burn with severity inhalation injury decreased and have difference compared with after 4 days. (P=0.033) Conclusion:1. Amount of fluid replacement ought to beyond to the amount of calculation according formula on severe burn with severity inhalation injury, especially to the first 24 hours after burn.2. Patients of severe burn with severity inhalation injury should have tracheostomy early resulting to decrease mortality.3. Mortality have silence decreased by early massive excision escharsion on deep burn with severity inhalation injury.