Study Of Protective Effect Of Ovateleaf Actinidia Leaf Extractive On Neurone After The Focal Cerebral Ischemia Of Rats

With the changes of living conditions and life style, the incidence rate of the ischemic cerebrovascular disease which also have the high rates of mortality and mutilation, have been highly increased ,and many medical scientific scholars has always took that as the research emphasis. Cooperating with other medical institutions ,we deeply studied the Actinidia kolomikta (Rupr.et Maxim.) Planch(AKP) which are planted in the Changbaishan region of Jilin province, and from those leaves we succeeded in extracting 9 kinds of flavonoids medical compositions Whose main structure has been approved the similarity to that of the Ginkgo biloba which has wildly been put into clinical use and confirmed by effective therapeutic action , thus considering the possibility of flavone extract to cure the cardiac and cerebrovascular disease, we studied the acute toxicology and pharmacodynamics of preclinical phase through three experiments. The first part was designed to determine LD50 and MTD, forty healthy ICR mice were chosen and randomly divided into four groups of different dosages which were diluted with AKP and...