Relative Risk Factors Of Colonization Of Methicillin-resistant Staphylococcus Aureus In Old Outpatients

ObjectiveCommunity infections caused by methicillin - resistant staphylococcus aureus ( MRSA) increasing .gradually in recent years have been proved closely rele-vant with colonization of MRSA in outpatients. To elucidate the relative risk factors of colonization of MRSA and further more ascertain the origin of colonized MRSA is in favour of prevention and treatment tragedy for MRSA infection.MethodsAll samples of nasal swabs from 372 outpatients during January to June 2005 were detected for both methicillin - susceptible staphylococcus aureus (MSSA) and methicillin - resistant staphylococcus aureus ( MRSA ) and divided into three groups;group MRSA, MSSA and non - SA ( staphylococcus aureus). Antibiotics sensitivity spectra were obtained from not only MRSA group but also the separate of inpatients at the same time. Questionaire about relative risk factors of colonization of MRSA were finished by all the outpatients in details.Results(1)11 from 372 old outpatients were found colonized with MRSA, the prevalence of MRSA colonization is 3 %. Patients with MSSA colonization were 200 (53. 8% ). (2) Accumulated clinic frequency ≥ 6 in the recent year, ceph-alosporins used during the recent 6 months and positive chronic respiratory diseases history are related with colonization of MRSA. (3) All strains of the colo-nized MRSA are strains of multidrug resistance. There was no obvious difference in the drug sensitivity spectra between MRSA colonized in outpatients and that from inpatients.DiscussionThis is the first paper to investigate MRSA colonization in old outpatients. The prevalence of MRSA colonization in old outpatients is relatively low(3% ) , and accounts 5.2% in the colonization of SA. The colonized MRSA in outpatients are most likely aquired from previous contact with medical care institutions. Our research indicates that the control of dissemination of MRSA in medical care institutions seems to be the key point in the tragedy of prevention.