| The paper stands for the investigation of the anti-fatigue effect of panaxoside Rg1 and provides the relative mechanism by a series of control experiments, which will contribute to the anti-fatigue preparation of ginsenoside Rgl for oral use. Furthermore, an optimum ratio of panaxoside Rgl and FDP and the existence of the greater cytoprotective action are expected to be determined through the observation of the change of biochemical indicator.The results show ginsenoxide Rgl could impact the anti-fatigue in some extent through oral, which was obvious when the low dose was applied. It was considered that the anti-fatigue of ginsenoside worked through several ways.i. It increased the store amount of glucogen and maintained the stability of BG;ii. It promoted the fat mobilization and used energy properly during the long-time exercise;iii. It decreased BUN and LA and also inhibited the accumulation of metabolic waste;iv, It Strengthened the activity of anti-oxidants;v. It regulated the metabolism of amino acid in brain. It was found that there was no interaction between ginsenoside Rgl and FDP since the combination of FDP did not prolong the swim duration of mice even though it could lessen the cell damage.
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